Celsion’s extensive oncology pipeline represents a comprehensive, integrated portfolio of targeted therapeutic agents, encompassing chemotherapy, immunotherapy, and RNA therapy.

Our Technologies

ThermoDox®, Celsion’s lead product candidate, incorporates Lyso-Thermosenstive Liposomal Doxorubicin (LTLDs), a unique liposomal technology that allows for the triggered release of a drug payload through low temperature (just above body temperature) heat activation.

TheraPlas™ is a versatile technology platform for the delivery of DNA and messenger RNA (mRNA) therapeutics via synthetic non-viral carriers and is uniquely capable of providing cell transfection capability for double-stranded DNA plasmids and large therapeutic RNA segments such as mRNA.

TheraSilence™ is a versatile technology platform focused on delivering synthetically generated small inhibitory RNAs (siRNAs), microRNAs, microRNA mimics, and related molecules that can regulate protein expression by exploiting endogenous cell mechanisms.


Celsion is a biopharmaceutical company dedicated to the research and development of innovative, targeted therapies that address unmet medical needs in oncology. With the recent acquisition of EGEN, Inc., Celsion has become a fully integrated company with an extensive, complementary, multi-phase clinical pipeline; platform technologies for the discovery of novel, nucleic acid-based immunotherapies and other anti-cancer DNA/RNA therapies; and expertise from bench to bedside. 

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